Finally, the authors compared the IP accumulation and intracellular Ca2+ release signaling pathways in both WT and 5-HT2A–S314A expressed in intact cells. Three 5-HT2A receptor agonists [5-HT, DOI, and α-methylserotonin (AMS)] all showed increased efficacy and potency in phosphorylation-deficient 5-HT2A–S314A fibroblasts, compared with WT receptors,...

The authors considered a large long-term care facility with over 100 beds, characterized by the presence of resident animals. The researchers collected nasal swabs from the animals for overall eight weeks. Two cats presented MRSA positive swabs and the test positivity was confirmed in subsequent...

Teens who volunteer in their community can keep each other motivated to participate. This involvement can lead to exposure to role models and eventually lead to the teens becoming positive role models themselves. Have you ever been pressured to have “one more drink,” or stay...

Five common symptoms of dehydration include tiredness, dry skin and lips, thirst, dark pee, and not peeing as often. Staying hydrated is as important to your health as eating, exercising, and sleeping well. It’s especially important at times when you’re more likely to lose fluids...

Additionally, they reported higher alcohol use and hostile sexism than those lower in mental rigidity. Self-awareness is important for everyone’s mental health, but it is especially necessary for people with AUD and anger issues. Understanding your emotions and making smart decisions about alcohol consumption is...